Dinitrobenzylidene-acyl-hydrazone-dihydroxyphenyl-cpd2n
Ki of 69.18 nM AChE
General
Type : Dinitrophenyl, Dihydroxyphenyl
Chemical_Nomenclature : (3,5-Dihydroxyphenyl)[(E)-2-[(2,4-dinitrophenyl)methylene]hydrazino]methanone
Canonical SMILES : C1=C(C(=CC(=C1)[N+](=O)[O-])[N+](=O)[O-])C=NNC(C2=CC(=CC(=C2)O)O)=O
InChI : InChI=1S\/C14H10N4O7\/c19-11-3-9(4-12(20)6-11)14(21)16-15-7-8-1-2-10(17(22)23)5-13(8)18(24)25\/h1-7,19-20H,(H,16,21)
InChIKey : FCXOPJVTLHCASN-UHFFFAOYSA-N
Other name(s) : Compound 2n
Target
Families : Dinitrobenzylidene-acyl-hydrazone-dihydroxyphenyl-cpd2n ligand of proteins in family
ACHE
Protein :
human-ACHE
References (1)
| Title : Discovery of Dual-Inhibitor Acyl Hydrazones for Acetylcholinesterase and Carbonic Anhydrase I\/II: A Mechanistic Insight into Alzheimer's Disease - Dincel_2025_ChemistrySelect_10_e202405876 |
| Author(s) : Dincel ED , Kuran ED , Demir Y , Sucu BO , Gulcin I , Ulusoy-Guzeldemirci N |
| Ref : ChemistrySelect , 10 :e202405876 , 2025 |
| Abstract : |
| PubMedSearch : Dincel_2025_ChemistrySelect_10_e202405876 |
| PubMedID: |