Fenchlorphos

General

Type : Organophosphate,Sulfur Compound

Chemical_Nomenclature : dimethoxy-sulfanylidene-(2,4,5-trichlorophenoxy)-$l^{5}-phosphane

Canonical SMILES : COP(=S)(OC)OC1=CC(=C(C=C1Cl)Cl)Cl

InChI : InChI=1S\/C8H8Cl3O3PS\/c1-12-15(16,13-2)14-8-4-6(10)5(9)3-7(8)11\/h3-4H,1-2H3

InChIKey : JHJOOSLFWRRSGU-UHFFFAOYSA-N

Other name(s) : O,O-dimethyl O-(2,4,5 trichlorophenyl phosphorothioate),Phenol, 2,4,5-trichloro-, O-ester with O,O-dimethyl phosphorothioate,Ronnel,Dermafos,Trichlormetaphos,Blitex,Fenchlorophos,Korlan,Ectoral,Etrolene,Gesektin K,Moorman's medicated RID-EZY,Nankor,Rovan,Trichlorometafos,Trolene,Viozene,Fenclofos


MW : 321.54

Formula : C8H8Cl3O3PS

CAS_number : 299-84-3

PubChem : 9298

UniChem : JHJOOSLFWRRSGU-UHFFFAOYSA-N

IUPHAR :

Wikipedia :

Target

Families : Fenchlorphos ligand of proteins in family: ACHE

Stucture :

Protein :

References (22)

Title : A pharmacological screen for compounds that rescue the developmental lethality of a Drosophila ATM mutant - Rimkus_2018_PLoS.One_13_e0190821
Author(s) : Rimkus SA , Wassarman DA
Ref : PLoS ONE , 13 :e0190821 , 2018
Abstract : Rimkus_2018_PLoS.One_13_e0190821
ESTHER : Rimkus_2018_PLoS.One_13_e0190821
PubMedSearch : Rimkus_2018_PLoS.One_13_e0190821
PubMedID: 29338042

Title : Determining organohalides in animal fats using gel permeation chromatographic cleanup: repeatability study - Goodspeed_1991_J.Assoc.Off.Anal.Chem_74_388
Author(s) : Goodspeed DP , Chestnut LI
Ref : J Assoc Off Analytical Chemistry , 74 :388 , 1991
Abstract : Goodspeed_1991_J.Assoc.Off.Anal.Chem_74_388
ESTHER : Goodspeed_1991_J.Assoc.Off.Anal.Chem_74_388
PubMedSearch : Goodspeed_1991_J.Assoc.Off.Anal.Chem_74_388
PubMedID: 2050618

Title : Cholinesterase activities in uterus of normal and fenchlorphos treated blue foxes (Alopex lagopus) during various reproductive states -
Author(s) : Berge GN , Sterri SH , Soli NE
Ref : Acta Vet Scand , 29 :117 , 1988
PubMedID: 2462338

Title : Effects of in vitro ronnel on metabolic activity in subcutaneous adipose tissue and skeletal muscle from steers - Trankina_1985_J.Anim.Sci_60_652
Author(s) : Trankina ML , Beitz DC , Trenkle AH
Ref : J Anim Sci , 60 :652 , 1985
Abstract : Trankina_1985_J.Anim.Sci_60_652
ESTHER : Trankina_1985_J.Anim.Sci_60_652
PubMedSearch : Trankina_1985_J.Anim.Sci_60_652
PubMedID: 2580822

Title : Changes in plasma concentrations of thyroxine, triiodothyronine, cholesterol and total lipid in beef steers fed ronnel - Rumsey_1983_J.Anim.Sci_56_125
Author(s) : Rumsey TS , Bitman J , Tao H
Ref : J Anim Sci , 56 :125 , 1983
Abstract : Rumsey_1983_J.Anim.Sci_56_125
ESTHER : Rumsey_1983_J.Anim.Sci_56_125
PubMedSearch : Rumsey_1983_J.Anim.Sci_56_125
PubMedID: 6186657

Title : Teratogenicity and embryotoxicity of orally administered fenchlorphos in blue foxes -
Author(s) : Berge GN , Nafstad I
Ref : Acta Vet Scand , 24 :99 , 1983
PubMedID: 6191556

Title : Ovarian and testicular function in the blue fox (Alopex lagopus) after oral administration of fenchlorphos during the breeding season -
Author(s) : Berge GN , Mondain-Monval M , Smith A , Moller OM
Ref : Acta Vet Scand , 24 :200 , 1983
PubMedID: 6193696

Title : Teratogenic effects of the organophosphorus compound fenchlorphos in rabbits -
Author(s) : Nafstad I , Berge G , Sannes E , Lyngset A
Ref : Acta Vet Scand , 24 :295 , 1983
PubMedID: 6197870

Title : Modification of brain mitochondrial enzymes by the oxygen analogue of ronnel at various stages of development and aging - Sitkiewicz_1982_J.Neurochem_39_1308
Author(s) : Sitkiewicz D , Skonieczna M , Rychla T , Gazdzik D , Podymniak S , Bicz W
Ref : Journal of Neurochemistry , 39 :1308 , 1982
Abstract : Sitkiewicz_1982_J.Neurochem_39_1308
ESTHER : Sitkiewicz_1982_J.Neurochem_39_1308
PubMedSearch : Sitkiewicz_1982_J.Neurochem_39_1308
PubMedID: 6181202

Title : Teratogenicity study on pyrethrum and rotenone (natural origin) and ronnel in pregnant rats - Khera_1982_J.Toxicol.Environ.Health_10_111
Author(s) : Khera KS , Whalen C , Angers G
Ref : J Toxicol Environ Health , 10 :111 , 1982
Abstract : Khera_1982_J.Toxicol.Environ.Health_10_111
ESTHER : Khera_1982_J.Toxicol.Environ.Health_10_111
PubMedSearch : Khera_1982_J.Toxicol.Environ.Health_10_111
PubMedID: 6182301

Title : [Histochemical studies on the effect of fenchlorphos (0,0-dimethyl-0- 2,4,5-trichlophenyl thiophosphate) on perfused liver of albino rat] -
Author(s) : Sawicki B , Kuczynski M , Mackowiak J , Derewonko S
Ref : Patol Pol , 32 :79 , 1981
PubMedID: 6171765

Title : Effects of ronnel on growth, endocrine function and blood measurements in steers and rats - Rumsey_1981_J.Anim.Sci_53_217
Author(s) : Rumsey TS , Tao H , Bitman J
Ref : J Anim Sci , 53 :217 , 1981
Abstract : Rumsey_1981_J.Anim.Sci_53_217
ESTHER : Rumsey_1981_J.Anim.Sci_53_217
PubMedSearch : Rumsey_1981_J.Anim.Sci_53_217
PubMedID: 6172413

Title : Effect of fenchlorphos intoxication on the respiration of brain mitochondria of rats at different age -
Author(s) : Sitkiewicz D , Gietka G , Bicz W
Ref : Neuropatol Pol , 19 :209 , 1981
PubMedID: 6170914

Title : [Determination of dermafos (fenchlorphos) residues in the tissues of hens and rabbits after single oral dose of pure and technical preparations] - Zasadowski_1981_Pol.Arch.Weter_23_143
Author(s) : Zasadowski A
Ref : Pol Arch Weter , 23 :143 , 1981
Abstract : Zasadowski_1981_Pol.Arch.Weter_23_143
ESTHER : Zasadowski_1981_Pol.Arch.Weter_23_143
PubMedSearch : Zasadowski_1981_Pol.Arch.Weter_23_143
PubMedID: 6170958

Title : Isolation and concentration of organophosphorus pesticides from drinking water at the ng\/L level, using macroreticular resin - LeBel_1979_J.Assoc.Off.Anal.Chem_62_241
Author(s) : LeBel GL , Williams DT , Griffith G , Benoit FM
Ref : J Assoc Off Analytical Chemistry , 62 :241 , 1979
Abstract : LeBel_1979_J.Assoc.Off.Anal.Chem_62_241
ESTHER : LeBel_1979_J.Assoc.Off.Anal.Chem_62_241
PubMedSearch : LeBel_1979_J.Assoc.Off.Anal.Chem_62_241
PubMedID: 447594

Title : The effect of O,O-dimethyl-O-(2,4,5-trichlorophenyl) phosphorothioate (fenchlorphos) on cholinesterases in the blue fox (Alopex lagopus) -
Author(s) : Soli NE , Andersen RA , Skaare JU , Mikalsen A
Ref : Acta Vet Scand , 18 :408 , 1977
PubMedID: 71852

Title : The activities of acetylcholinesterase, alkaline phosphatase and acid phosphatase of the rat brain following fenchlorphos intoxication -
Author(s) : Sulinski A , Skalska E , Obrusiewicz K
Ref : Neuropatol Pol , 14 :451 , 1976
PubMedID: 63924

Title : The activities of some oxidoreductases and respiratory control in rat brain mitochondria following fenchlorphos intoxication -
Author(s) : Rakowska I , Dybowska A , Malatynska E , Kielducka A
Ref : Neuropatol Pol , 14 :461 , 1976
PubMedID: 63925

Title : [Histochemical study of the effect of phosphoroorganic esters Z-50 (fenchlorfos) and Z-51 (bromophos) on cholinesteras activity in the course of the muscle phase in experimental trichinellosis in mice] - Ramisz_1975_Pol.Arch.Weter_17_623
Author(s) : Ramisz A , Komorowski A
Ref : Pol Arch Weter , 17 :623 , 1975
Abstract : Ramisz_1975_Pol.Arch.Weter_17_623
ESTHER : Ramisz_1975_Pol.Arch.Weter_17_623
PubMedSearch : Ramisz_1975_Pol.Arch.Weter_17_623
PubMedID: 52151

Title : Problems of housefly (Musca domestica) control due to multiresistance to insesticides - Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340
Author(s) : Keiding J
Ref : J Hyg Epidemiol Microbiol Immunol , 19 :340 , 1975
Abstract : Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340
ESTHER : Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340
PubMedSearch : Keiding_1975_J.Hyg.Epidemiol.Microbiol.Immunol_19_340
PubMedID: 52667

Title : Studies on the effect of Fenchlorphos on postirradiation changes of serum proteins and nucleic acids content in rat liver - Mackowiak_1975_Strahlentherapie_150_97
Author(s) : Mackowiak J , Wisniewski K
Ref : Strahlentherapie , 150 :97 , 1975
Abstract : Mackowiak_1975_Strahlentherapie_150_97
ESTHER : Mackowiak_1975_Strahlentherapie_150_97
PubMedSearch : Mackowiak_1975_Strahlentherapie_150_97
PubMedID: 52206

Title : [Absorption, tissue distribution and excretion of O,O-dimethyl-O-2,4,5- trichlorphenyl-phosphorothioate (Fenchlorphos) in rats] -
Author(s) : Palut D , Grzymala W
Ref : Rocz Panstw Zakl Hig , 22 :591 , 1971
PubMedID: 4109663