Galangin
Galangin, the main active component of Alpinia officinarum Hance is a growth inhibitor of breast tumor cells. It has a role as an antimicrobial agent, an EC 3.1.1.3 (triacylglycerol lipase) inhibitor and a plant metabolite
General
Type : Natural, Flavonoid, Chromen
Chemical_Nomenclature : 3,5,7-trihydroxy-2-phenylchromen-4-one
Canonical SMILES : C1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O
InChI : InChI=1S\/C15H10O5\/c16-9-6-10(17)12-11(7-9)20-15(14(19)13(12)18)8-4-2-1-3-5-8\/h1-7,16-17,19H
InChIKey : VCCRNZQBSJXYJD-UHFFFAOYSA-N
Other name(s) : Norizalpinin || 3,5,7-Trihydroxyflavone || 3,5,7-Trihydroxy-2-phenyl-4H-chromen-4-one
MW : 270.24
Formula : C15H10O5
CAS_number : 548-83-4
PubChem : 5281616
UniChem : VCCRNZQBSJXYJD-UHFFFAOYSA-N
Wikipedia : Galangin
Target
Families : Galangin ligand of proteins in family
Fungal-Bact_LIP
Pancreatic_lipase
Protein :
canpa-LIP2
References (4)
| Title : Inhibition of CpLIP2 Lipase Hydrolytic Activity by Four Flavonols (Galangin, Kaempferol, Quercetin, Myricetin) Compared to Orlistat and Their Binding Mechanisms Studied by Quenching of Fluorescence - Nasri_2019_Molecules_24_ |
| Author(s) : Nasri R , Bidel LPR , Rugani N , Perrier V , Carriere F , Dubreucq E , Jay-Allemand C |
| Ref : Molecules , 24 : , 2019 |
| Abstract : |
| PubMedSearch : Nasri_2019_Molecules_24_ |
| PubMedID: 31398944 |
| Gene_locus related to this paper: canpa-LIP2 |
| Title : Prediction of comparative inhibition efficiency for a novel natural ligand, galangin against human brain acetylcholinesterase, butyrylcholinesterase and 5-lipoxygenase: a neuroinformatics study - Shaikh_2014_CNS.Neurol.Disord.Drug.Targets_13_452 |
| Author(s) : Shaikh S , Ahmad SS , Ansari MA , Shakil S , Rizvi SM , Tabrez S , Akhtar S , Kamal MA |
| Ref : CNS Neurol Disord Drug Targets , 13 :452 , 2014 |
| Abstract : |
| PubMedSearch : Shaikh_2014_CNS.Neurol.Disord.Drug.Targets_13_452 |
| PubMedID: 24059300 |
| Title : Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats - Kumar_2013_Pharm.Biol_51_607 |
| Author(s) : Kumar S , Alagawadi KR |
| Ref : Pharm Biol , 51 :607 , 2013 |
| Abstract : |
| PubMedSearch : Kumar_2013_Pharm.Biol_51_607 |
| PubMedID: 23363068 |
| Title : Galangin, a flavonol derived from Rhizoma Alpiniae Officinarum, inhibits acetylcholinesterase activity in vitro - Guo_2010_Chem.Biol.Interact_187_246 |
| Author(s) : Guo AJ , Xie HQ , Choi RC , Zheng KY , Bi CWC , Xu SL , Dong TTX , Tsim KWK |
| Ref : Chemico-Biological Interactions , 187 :246 , 2010 |
| Abstract : |
| PubMedSearch : Guo_2010_Chem.Biol.Interact_187_246 |
| PubMedID: 20452337 |