Gene Locus : bovin-thyro
Mode of mutation : Site directed mutagenesis
Disease :
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : No torpedo number
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
The long range disulfide bond C408-C608 (200 aa loop) is situated in the N-term part of the TG well upstrem of the cholinesterase like domain. Both mutations or double mutation did not decrease the secretion
| Title : Structural Features of Thyroglobulin Linked to Protein Trafficking - Citterio_2023_Protein.Sci__e4784 |
| Author(s) : Citterio CE , Kim K , Rajesh B , Pena K , Clarke OB , Arvan P |
| Ref : Protein Science , :e4784 , 2023 |
| Abstract : |
| PubMedSearch : Citterio_2023_Protein.Sci__e4784 |
| PubMedID: 37717261 |
| Gene_locus related to this paper: bovin-thyro , human-TG |