E334Q_human-ACHE

General

Gene Locus : human-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Catalysis no activity Shafferman_2005_Chem.Biol.Interact_157-158_123

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Catalysis

Torpedo_number : 327

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
E334Q p.Glu334Gln (E365Q p.Glu365Gln in primary sequence with 31 amino-acids signal peptide) Catalytic triad Catalysis\;no activity

References (1)

Title : Functional requirements for the optimal catalytic configuration of the AChE active center - Shafferman_2005_Chem.Biol.Interact_157-158_123
Author(s) : Shafferman A , Barak D , Kaplan D , Ordentlich A , Kronman C , Velan B
Ref : Chemico-Biological Interactions , 157-158 :123 , 2005
PubMedID: 16256968