G142S_boomi-ACHE1

General

Gene Locus : boomi-ACHE1

Mode of mutation : Site directed mutagenesis

Disease :

Summary : OP-resistance May Contribute to OP-resistance Temeyer_2019_J.Med.Entomol_56_1318

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : 119

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
Site directed mutation G142S results in 500-2000-fold decreased sensitivity to OP inhibition

References (1)

Title : Baculoviral Expression of Presumptive OP-Resistance Mutations in BmAChE1 of Rhipicephalus (Boophilus) microplus (Ixodida: Ixodidae) and Biochemical Resistance to OP Inhibition - Temeyer_2019_J.Med.Entomol_56_1318
Author(s) : Temeyer KB , Schlechte KG , McDonough WP
Ref : Journal of Medical Entomology , 56 :1318 , 2019
Abstract :
PubMedSearch : Temeyer_2019_J.Med.Entomol_56_1318
PubMedID: 31102447
Gene_locus related to this paper: boomi-ACHE1