boomi-ACHE1

Rhipicephalus microplus (Cattle tick) (Boophilus microplus) acetylcholinesterase 1

Comment

The following mutations were found associated with OP resistant strains, but were also found in susceptible strains and were not characterized biochemically. Consequently they are not introduced individually in ESTHER\; P157S, E195G, Y230C, S282G, T362A, L417P, Q488R, I493T, W571R, W571F see Swale et al. 2013 Temeyer 2018

Relationship

Family : ACHE

Block : C

Position in NCBI Life Tree : Boophilus microplus

(Below N is a link to NCBI taxonomic web page and E link to ESTHER at designed phylum.)

> cellular organisms N E > Eukaryota N E > Opisthokonta N E > Metazoa N E > Eumetazoa N E > Bilateria N E > Protostomia N E > Ecdysozoa N E > Panarthropoda N E > Arthropoda N E > Chelicerata N E > Arachnida N E > Acari N E > Parasitiformes N E > Ixodida N E > Ixodoidea N E > Ixodidae N E > Rhipicephalinae N E > Rhipicephalus [genus] N E > Boophilus N E > Rhipicephalus microplus N E

Molecular evidence

No mutation

No structure

No kinetic

No disease

No substrate

No inhibitor

Database

Sequence

Peptide

MDPEQDMLHE NLASCHLTLL ALLVCGGVVL RCLSIEPEED ASNRVEDQDA EDPVETVVVE TAWGPVKGFI AQSPLGKPVR VFYGIPYAKP PTGKRRFDRA ESIEEPWTDV LDATVKPNSC FQVLDTLYGN FSGSTMWNAN TEMSEDCLKL NVWAPGPPTS SGGRPLAVLV WIYGGGFYSG TSTLDVYDAR TLVSEENVVV VSMNYRVASL GFLSFGNETL PGNAGLYDQY MALKWVQENV AAFGGDPDRV TLFGESAGAA SAGLHVLSPL SESLFHRVIL QSGSPAVPWG FQDRDKARQS AKKLATALRA PDSLDQETLD SLRCERPEDI VNNETNSGGV VDFPFVPVAD GVFLPDTPQA LTDKGSFARN ISVMLGSNAN EGSWFLQYFF GFPVTDETPE VTKENFTAVL EALDPSLEQT PIAEIMKTYT AGEIPSTAAD ILKALDSIVG DYHFTCPVVR WADTFARAGI PVYQYVFARR SSQNPWPQWT GVIHGEEVPF VFGEPLNDTY CYSEEDKTLS RRIMRYWANF AKTGNPNLPE DGSPGSTIRW PERTDSLKRH LVLDVNESVG WAHRQTYCDF WENVRRNRTP PVPSC

References (8)

Title : Baculoviral Expression of Presumptive OP-Resistance Mutations in BmAChE1 of Rhipicephalus (Boophilus) microplus (Ixodida: Ixodidae) and Biochemical Resistance to OP Inhibition - Temeyer_2019_J.Med.Entomol_56_1318
Author(s) : Temeyer KB , Schlechte KG , McDonough WP
Ref : Journal of Medical Entomology , 56 :1318 , 2019
PubMedID: 31102447
Gene_locus related to this paper: boomi-ACHE1

Title : Molecular biology of tick acetylcholinesterases - Temeyer_2018_Front.Biosci.(Landmark.Ed)_23_1320
Author(s) : Temeyer KB
Ref : Front Biosci (Landmark Ed) , 23 :1320 , 2018
PubMedID: 28930602
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Inhibitor profile of (n)-tacrines -methylcarbamates on acetylcholinesterase from Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi - Swale_2013_Pestic.Biochem.Physiol_106_
Author(s) : Swale DR , Tong F , Temeyer KB , Li A , Lam PC , Totrov MM , Carlier PR , Perez de Leon AA , Bloomquist JR
Ref : Pesticide Biochemistry and Physiology , 106 : , 2013
PubMedID: 24187393
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Acetylcholinesterase of Rhipicephalus (Boophilus) microplus and Phlebotomus papatasi: Gene identification, expression, and biochemical properties of recombinant proteins - Temeyer_2013_Pestic.Biochem.Physiol_106_118
Author(s) : Temeyer KB , Olafson PU , Brake DK , Tuckow AP , Li AY , Perez de Leon AA
Ref : Pesticide Biochemistry and Physiology , 106 :118 , 2013
PubMedID:
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Sequence polymorphism in acetylcholinesterase transcripts and genotyping survey of BmAchE1 in laboratory and Mexican strains of Rhipicephalus (Boophilus) microplus - Temeyer_2012_J.Med.Entomol_49_555
Author(s) : Temeyer KB , Olafson PU , Pruett JH
Ref : Journal of Medical Entomology , 49 :555 , 2012
PubMedID: 22679862
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Genetic factors potentially reducing fitness cost of organophosphate insensitive acetylcholinesterase(s) in Rhipicephalus (Boophilus) microplus - Temeyer_2011_Zoosymposia_6_260
Author(s) : Temeyer KB , Tijerina MA , Davey RB , Olafson PU
Ref : Zoosymposia , 6 :260 , 2011
PubMedID:
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Baculovirus expression, biochemical characterization and organophosphate sensitivity of rBmAChE1, rBmAChE2, and rBmAChE3 of Rhipicephalus (Boophilus) microplus - Temeyer_2010_Vet.Parasitol_172_114
Author(s) : Temeyer KB , Pruett JH , Olafson PU
Ref : Vet Parasitol , 172 :114 , 2010
PubMedID: 20451328
Gene_locus related to this paper: boomi-ACHE1 , boomi-ACHE2 , boomi-ACHE3

Title : Acetylcholinesterase cDNA of the cattle tick, Boophilus microplus: characterisation and role in organophosphate resistance - Baxter_1998_Insect.Biochem.Mol.Biol_28_581
Author(s) : Baxter GD , Barker SC
Ref : Insect Biochemistry & Molecular Biology , 28 :581 , 1998
PubMedID: 9753768
Gene_locus related to this paper: boomi-ACHE1