L280H_eleel-ACHE

General

Gene Locus : eleel-ACHE

Mode of mutation : Site directed mutagenesis

Disease :

Summary : Fab epitope\;abolished inhibition by Elec-403\;Simon_1999_J.Biol.Chem_274_27740

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : Fab epitope

Torpedo_number : 280

Kinetic Parameter : No kinetic parameter

News : No news

Comment : "mutation with torpedo numbering" || "p.Leu280His"

References (1)

Title : The binding sites of inhibitory monoclonal antibodies on acetylcholinesterase. Identification of a novel regulatory site at the putative back door - Simon_1999_J.Biol.Chem_274_27740
Author(s) : Simon S , Le Goff A , Frobert Y , Grassi J , Massoulie J
Ref : Journal of Biological Chemistry , 274 :27740 , 1999
Abstract : Simon_1999_J.Biol.Chem_274_27740
ESTHER : Simon_1999_J.Biol.Chem_274_27740
PubMedSearch : Simon_1999_J.Biol.Chem_274_27740
PubMedID: 10488117