Gene Locus : horse-BCHE
Mode of mutation : Natural mutant
Disease :
Summary :
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification :
Torpedo_number : 1
Kinetic Parameter : No kinetic parameter
News : No news
Comment :
Mutation in the signal peptide. Torpedo_number could be 1 or -3. Adaptive variation in butyrylcholinesterase-influenced lipid metabolism during horse domestication. Influence on lipid metabolism. A missense mutation (ECA19:9,198,989, G>C). The lysine (K) residue is ancestral and widely conserved across mammals, the horse reference genome, which derives from a Thoroughbred individual, carry the derived G allele, encoding an asparagine (N) residue
| Title : Adaptive variation in butyrylcholinesterase-influenced lipid metabolism during horse domestication - Zhang_2026_Cell.Rep_45_117879 |
| Author(s) : Zhang Y , Liu X , Wang X , Yu Y , Jia Y , Pu Y , Ma Y , Orlando L , Jiang L |
| Ref : Cell Rep , 45 :117879 , 2026 |
| Abstract : |
| PubMedSearch : Zhang_2026_Cell.Rep_45_117879 |
| PubMedID: 42623242 |
| Gene_locus related to this paper: horse-BCHE |