Y591PfsX26_human-DAGLB

General

Gene Locus : human-DAGLB, human-DAGLB, human-DAGLB

Mode of mutation : Natural mutant

Disease : Parkinson disease, autosomal recessive (ARPD) early-onset (EOPD)

Summary :

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification :

Torpedo_number : No torpedo number

Kinetic Parameter : No kinetic parameter

News : No news

Comment :
homozygous frameshift variant (c.1770_1771del, p.Tyr591ProfsTer26), which was predicted to be pathogenic

References (3)

Title : Identification of DAGLB variants in Japanese early-onset Parkinson's disease - Luo_2025_J.Neural.Transm.(Vienna)__
Author(s) : Luo Y , Funayama M , Hatano T , Li Y , Yoshino H , Yamashita S , Mori A , Nakamura R , Hashizume Y , Yoshida M , Riku Y , Kanzato N , Hattori N
Ref : J Neural Transm (Vienna) , : , 2025
Abstract :
PubMedSearch : Luo_2025_J.Neural.Transm.(Vienna)__
PubMedID: 40244389
Gene_locus related to this paper: human-DAGLB

Title : Identification of DAGLB variants in Japanese early-onset Parkinson's disease - Luo_2025_J.Neural.Transm.(Vienna)__
Author(s) : Luo Y , Funayama M , Hatano T , Li Y , Yoshino H , Yamashita S , Mori A , Nakamura R , Hashizume Y , Yoshida M , Riku Y , Kanzato N , Hattori N
Ref : J Neural Transm (Vienna) , : , 2025
Abstract :
PubMedSearch : Luo_2025_J.Neural.Transm.(Vienna)__
PubMedID: 40244389
Gene_locus related to this paper: human-DAGLB

Title : Identification of DAGLB variants in Japanese early-onset Parkinson's disease - Luo_2025_J.Neural.Transm.(Vienna)__
Author(s) : Luo Y , Funayama M , Hatano T , Li Y , Yoshino H , Yamashita S , Mori A , Nakamura R , Hashizume Y , Yoshida M , Riku Y , Kanzato N , Hattori N
Ref : J Neural Transm (Vienna) , : , 2025
Abstract :
PubMedSearch : Luo_2025_J.Neural.Transm.(Vienna)__
PubMedID: 40244389
Gene_locus related to this paper: human-DAGLB