F358S_9cucu-ACHE1

General

Gene Locus : 9cucu-ACHE1

Mode of mutation : Natural mutant

Disease :

Summary : OP-resistance Wang_2017_Bull.Entomol.Res__1

AAA Change :

Allelic Variant :

Risk Factor :

Inhibitor :

Structure :

Disease by interaction :

Interact Gene Locus :

Xenobiotic sensitivity :

Modification : OP-resistance

Torpedo_number : 290

Kinetic Parameter : No kinetic parameter

News : No news

Comment : Five AA in the ace1 of R P. japonica differed from those found in S P. japonica. F358S, located in the acyl-binding pocket, might play a crucial role in the resistance of the insect to organophosphates (OPs). Others: K493E and I538V, close to conserved aromatic amino acids (i.e., H509, Y511, and W499) in the gorge, and G571R and T576A

References (1)

Title : Identification and characterization of ace1-type acetylcholinesterase in insecticide-resistant and -susceptible Propylaea japonica (Thunberg) - Wang_2017_Bull.Entomol.Res__1
Author(s) : Wang MM , Xing LY , Ni ZW , Wu G
Ref : Bull Entomol Res , :1 , 2017
Abstract : Wang_2017_Bull.Entomol.Res__1
ESTHER : Wang_2017_Bull.Entomol.Res__1
PubMedSearch : Wang_2017_Bull.Entomol.Res__1
PubMedID: 28747242
Gene_locus related to this paper: 9cucu-ACHE1