Gene Locus : lepsm-ACHE1A
Mode of mutation : Natural mutant
Disease :
Summary : OP-resistance azamethiphos resistance Kaur_2015_PLos.One_10_e0124220
AAA Change :
Allelic Variant :
Risk Factor :
Inhibitor :
Structure :
Disease by interaction :
Interact Gene Locus :
Xenobiotic sensitivity :
Modification : OP-resistance
Torpedo_number : 331
Kinetic Parameter : No kinetic parameter
News : April-22-2015
Comment : Mutation found in one of the two copies of ace1 in this species of copepod. It could play a role in azamethiphos sensivity. The position is 362 in the protein corresponding to 331 in Torpedo. The mutation pre-dates organophosphate use in salmon farming || p.Phe331Tyr F331Y F362Y
| Title : The mechanism (Phe362Tyr mutation) behind resistance in Lepeophtheirus salmonis pre-dates organophosphate use in salmon farming - Kaur_2017_Sci.Rep_7_12349 |
| Author(s) : Kaur K , Besnier F , Glover KA , Nilsen F , Aspehaug VT , Fjortoft HB , Horsberg TE |
| Ref : Sci Rep , 7 :12349 , 2017 |
| Abstract : Kaur_2017_Sci.Rep_7_12349 |
| ESTHER : Kaur_2017_Sci.Rep_7_12349 |
| PubMedSearch : Kaur_2017_Sci.Rep_7_12349 |
| PubMedID: 28955050 |
| Gene_locus related to this paper: lepsm-ACHE1A |
| Title : Phe362Tyr in AChE: A Major Factor Responsible for Azamethiphos Resistance in Lepeophtheirus salmonis in Norway - Kaur_2016_PLoS.One_11_e0149264 |
| Author(s) : Kaur K , Jansen PA , Aspehaug VT , Horsberg TE |
| Ref : PLoS ONE , 11 :e0149264 , 2016 |
| Abstract : Kaur_2016_PLoS.One_11_e0149264 |
| ESTHER : Kaur_2016_PLoS.One_11_e0149264 |
| PubMedSearch : Kaur_2016_PLoS.One_11_e0149264 |
| PubMedID: 26882536 |
| Title : Mechanism behind Resistance against the Organophosphate Azamethiphos in Salmon Lice (Lepeophtheirus salmonis) - Kaur_2015_PLoS.One_10_e0124220 |
| Author(s) : Kaur K , Helgesen KO , Bakke MJ , Horsberg TE |
| Ref : PLoS ONE , 10 :e0124220 , 2015 |
| Abstract : Kaur_2015_PLoS.One_10_e0124220 |
| ESTHER : Kaur_2015_PLoS.One_10_e0124220 |
| PubMedSearch : Kaur_2015_PLoS.One_10_e0124220 |
| PubMedID: 25893248 |
| Gene_locus related to this paper: lepsm-ACHE1A , lepsm-ACHE1B |