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Mutation Report for: Q643R_bacdo-ACHE

Mode of mutation|Natural mutant
Amino Acid change|Q643R
Torpedo number|553
Comment|In the resistant strain analysed I214V G488S Q643R are associated and homozygous. The position 643 in B. dorsalis is not homologous to Torpedo AChE
Kinetic parameters|none

    Title: Discovery of genes related to formothion resistance in oriental fruit fly (Bactrocera dorsalis) by a constrained functional genomics analysis
    Kuo TC, Hu CC, Chien TY, Chen MJ, Feng HT, Chen LF, Chen CY, Hsu JC
    Ref: Insect Molecular Biology, 24:338, 2015 : PubMed


    Title: Mutations in the acetylcholinesterase gene of Bactrocera dorsalis associated with resistance to organophosphorus insecticides
    Hsu JC, Haymer DS, Wu WJ, Feng HT
    Ref: Insect Biochemistry & Molecular Biology, 36:396, 2006 : PubMed


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Mail to: Nicolas Lenfant, Thierry Hotelier, Yves Bourne, Pascale Marchot and Arnaud Chatonnet.
Please cite: Lenfant 2013 Nucleic.Acids.Res. or Marchot Chatonnet 2012 Prot.Pept Lett.
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