Aarli_1975_Scand.J.Immunol_4_849

Reference

Title : Antibodies against nicotinic acetylcholine receptor and skeletal muscle in human and experimental myasthenia gravis - Aarli_1975_Scand.J.Immunol_4_849
Author(s) : Aarli JA , Mattsson C , Heilbronn E
Ref : Scand J Immunol , 4 :849 , 1975
Abstract : Using rocket immunoelectrophoresis and indirect haemagglutination tests, antibodies to nicotinic acetylcholine receptor (n-AChR) from Torpedo marmorata were detected in sera from rabbits with experimental myasthenia but not in sera from patients with myasthenia gravis or in rabbit antisera to a partly purified skeletal muscle antigen. Antibodies to this antigen were demonstrated in sera from patients with myasthenia gravis but not in sera from rabbits with experimental myasthenia. The results indicate that there is no immunological cross-reaction between the muscle antigen and n-AChR from Torpedo marmorata, and little or no cross-reactivity between these n-AChR antibodies and possible muscle n-AChR antibodies in myasthenia gravis patients.
ESTHER : Aarli_1975_Scand.J.Immunol_4_849
PubMedSearch : Aarli_1975_Scand.J.Immunol_4_849
PubMedID: 1215840

Related information

Citations formats

Aarli JA, Mattsson C, Heilbronn E (1975)
Antibodies against nicotinic acetylcholine receptor and skeletal muscle in human and experimental myasthenia gravis
Scand J Immunol 4 :849

Aarli JA, Mattsson C, Heilbronn E (1975)
Scand J Immunol 4 :849