| Title : A note on suxamethonium sensitivity and serum cholinesterase variants - Agarwal_1976_Hum.Genet_32_85 |
| Author(s) : Agarwal DP , Srivastava LM , Goedde HW |
| Ref : Hum Genet , 32 :85 , 1976 |
|
Abstract :
Sera from 21 cases of prolonged apnoea which showed normal phenotype (UU) on the basis of dibucaine and fluoride inhibition were re-examined by replacing the substrate benzoylcholine with succinylcholine (suxamethonium). 9 samples had normal enzyme activity but low dibucaine number (DN = less than 20) indicating the atypical variant; 6 sera showed no detectable enzyme activity. The remaining 6 samples had enzyme activity and DN comparable with healthy controls. The occurence of new variants of serum cholinesterase sensitive only to succinylcholine is suggested. |
| PubMedSearch : Agarwal_1976_Hum.Genet_32_85 |
| PubMedID: 1262027 |
Agarwal DP, Srivastava LM, Goedde HW (1976)
A note on suxamethonium sensitivity and serum cholinesterase variants
Hum Genet
32 :85
Agarwal DP, Srivastava LM, Goedde HW (1976)
Hum Genet
32 :85