Title : Symptomatic and nonamyloid\/tau based pharmacologic treatment for Alzheimer disease - Aisen_2012_Cold.Spring.Harb.Perspect.Med_2_a006395 |
Author(s) : Aisen PS , Cummings J , Schneider LS |
Ref : Cold Spring Harb Perspect Med , 2 :a006395 , 2012 |
Abstract :
In this work we consider marketed drugs for Alzheimer disease (AD) including acetylcholinesterase inhibitors (AChE-Is) and antiglutamatergic treatment involving the N-methyl-d-aspartate (NMDA) receptor. We discuss medications and substances available for use as cognitive enhancers that are not approved for AD or cognitive impairment, and other neurotransmitter-related therapies in development or currently being researched. We also review putative therapies that aim to slow disease progression by mechanisms not directly related to amyloid or tau. |
PubMedSearch : Aisen_2012_Cold.Spring.Harb.Perspect.Med_2_a006395 |
PubMedID: 22393531 |
Aisen PS, Cummings J, Schneider LS (2012)
Symptomatic and nonamyloid\/tau based pharmacologic treatment for Alzheimer disease
Cold Spring Harb Perspect Med
2 :a006395
Aisen PS, Cummings J, Schneider LS (2012)
Cold Spring Harb Perspect Med
2 :a006395