| Title : Lipase-catalyzed domino kinetic resolution of alpha-hydroxynitrones\/intramolecular 1,3-dipolar cycloaddition: a concise asymmetric total synthesis of (-)-rosmarinecine - Akai_2005_Chem.Commun.(Camb)__2369 |
| Author(s) : Akai S , Tanimoto K , Kanao Y , Omura S , Kita Y |
| Ref : Chem Commun (Camb) , :2369 , 2005 |
|
Abstract :
The title domino reactions were developed to directly provide tetrahydrofuro[3,4-c]isoxazole derivatives (5 and 9) in > or =90% ee from racemic alpha-hydroxynitrones (2 and 6), which were used in the concise asymmetric total synthesis of (-)-rosmarinecine . |
| PubMedSearch : Akai_2005_Chem.Commun.(Camb)__2369 |
| PubMedID: 15877131 |
Akai S, Tanimoto K, Kanao Y, Omura S, Kita Y (2005)
Lipase-catalyzed domino kinetic resolution of alpha-hydroxynitrones\/intramolecular 1,3-dipolar cycloaddition: a concise asymmetric total synthesis of (-)-rosmarinecine
Chem Commun (Camb)
:2369
Akai S, Tanimoto K, Kanao Y, Omura S, Kita Y (2005)
Chem Commun (Camb)
:2369