| Title : One-pot synthesis of optically active allyl esters via lipase-vanadium combo catalysis - Akai_2010_Org.Lett_12_4900 |
| Author(s) : Akai S , Hanada R , Fujiwara N , Kita Y , Egi M |
| Ref : Org Lett , 12 :4900 , 2010 |
|
Abstract :
The combination of vanadium-oxo compounds (3 or 4) with a lipase produced the regio- and enantioconvergent transformation of racemic allyl alcohols (1 or 2) into optically active allyl esters. In this system, the vanadium compounds catalyzed the continuous racemization of the alcohols along with the transposition of the hydroxyl group, while the lipase effected the chemo- and enantioselective esterification to achieve the dynamic kinetic resolution. |
| PubMedSearch : Akai_2010_Org.Lett_12_4900 |
| PubMedID: 20936813 |
Akai S, Hanada R, Fujiwara N, Kita Y, Egi M (2010)
One-pot synthesis of optically active allyl esters via lipase-vanadium combo catalysis
Org Lett
12 :4900
Akai S, Hanada R, Fujiwara N, Kita Y, Egi M (2010)
Org Lett
12 :4900