Alder_2012_Science_335_1348

Reference

Title : The path from beta-carotene to carlactone, a strigolactone-like plant hormone - Alder_2012_Science_335_1348
Author(s) : Alder A , Jamil M , Marzorati M , Bruno M , Vermathen M , Bigler P , Ghisla S , Bouwmeester H , Beyer P , Al-Babili S
Ref : Science , 335 :1348 , 2012
Abstract : Strigolactones, phytohormones with diverse signaling activities, have a common structure consisting of two lactones connected by an enol-ether bridge. Strigolactones derive from carotenoids via a pathway involving the carotenoid cleavage dioxygenases 7 and 8 (CCD7 and CCD8) and the iron-binding protein D27. We show that D27 is a beta-carotene isomerase that converts all-trans-beta-carotene into 9-cis-beta-carotene, which is cleaved by CCD7 into a 9-cis-configured aldehyde. CCD8 incorporates three oxygens into 9-cis-beta-apo-10'-carotenal and performs molecular rearrangement, linking carotenoids with strigolactones and producing carlactone, a compound with strigolactone-like biological activities. Knowledge of the structure of carlactone will be crucial for understanding the biology of strigolactones and may have applications in combating parasitic weeds.
ESTHER : Alder_2012_Science_335_1348
PubMedSearch : Alder_2012_Science_335_1348
PubMedID: 22422982

Related information

Substrate Carlactone

Citations formats

Alder A, Jamil M, Marzorati M, Bruno M, Vermathen M, Bigler P, Ghisla S, Bouwmeester H, Beyer P, Al-Babili S (2012)
The path from beta-carotene to carlactone, a strigolactone-like plant hormone
Science 335 :1348

Alder A, Jamil M, Marzorati M, Bruno M, Vermathen M, Bigler P, Ghisla S, Bouwmeester H, Beyer P, Al-Babili S (2012)
Science 335 :1348