| Title : Two new cholinesterase inhibitors asiatoates A and B from Buddleja asiatica - Ali_2013_J.Asian.Nat.Prod.Res_15_631 |
| Author(s) : Ali F , Khan HU , Afzal M , Samad A , Khan SU , Ali I |
| Ref : J Asian Nat Prod Res , 15 :631 , 2013 |
|
Abstract :
Two new benzoates, asiatoate A (1) and asiatoate B (2), have been isolated from the ethyl acetate soluble fraction of Buddleja asiatica whole plant. Their structures were elucidated with the help of spectroscopic data. Both showed significant inhibitory effect on acetylcholinesterase (AChE) and butylcholinesterase (BChE) in a dose-dependent manner. The IC50 values of compounds 1-2 were 5.54 and 8.34 muM against AChE while 30.94 and 35.94 muM against BChE, respectively. |
| PubMedSearch : Ali_2013_J.Asian.Nat.Prod.Res_15_631 |
| PubMedID: 23659547 |
Ali F, Khan HU, Afzal M, Samad A, Khan SU, Ali I (2013)
Two new cholinesterase inhibitors asiatoates A and B from Buddleja asiatica
J Asian Nat Prod Res
15 :631
Ali F, Khan HU, Afzal M, Samad A, Khan SU, Ali I (2013)
J Asian Nat Prod Res
15 :631