| Title : A trisialoganglioside containing a sialyl alpha 2-6 N- acetylgalactosamine residue is a cholinergic-specific antigen, Chol-1 alpha - Ando_1992_J.Biochem_111_287 |
| Author(s) : Ando S , Hirabayashi Y , Kon K , Inagaki F , Tate S , Whittaker VP |
| Ref : J Biochem , 111 :287 , 1992 |
|
Abstract :
Cholinergic-specific antigens termed the Chol-1 family have been suggested to be of a ganglioside nature by Richardson et al. (J. Neurochem. 38, 1605-1614, 1982). Two molecular species of polysialogangliosides among bovine brain gangliosides were found to react with anti-Chol-1 alpha antiserum. One of them, Chol-1 alpha-a, was isolated and characterized as a trisialoganglioside containing the gangliotetraose backbone in which 1 mol of sialic acid was attached to each of the reducing end galactose, N-acetylgalactosamine and internal galactose residues, respectively. The chemical structure of Chol-1 alpha-a was determined for the first time, being as follows: IV3NeuAc III6NeuAc II3NeuAc-GgOse4 Cer. |
| PubMedSearch : Ando_1992_J.Biochem_111_287 |
| PubMedID: 1587788 |
Ando S, Hirabayashi Y, Kon K, Inagaki F, Tate S, Whittaker VP (1992)
A trisialoganglioside containing a sialyl alpha 2-6 N- acetylgalactosamine residue is a cholinergic-specific antigen, Chol-1 alpha
J Biochem
111 :287
Ando S, Hirabayashi Y, Kon K, Inagaki F, Tate S, Whittaker VP (1992)
J Biochem
111 :287