| Title : Cholinesterase inhibitors lack therapeutic effect in amyotrophic lateral sclerosis. A controlled study of physostigmine versus neostigmine - Aquilonius_1986_Acta.Neurol.Scand_73_628 |
| Author(s) : Aquilonius SM , Askmark H , Eckernas SA , Gillberg PG , Hilton-Brown P , Rydin E , Stalberg E |
| Ref : Acta Neurologica Scandinavica , 73 :628 , 1986 |
|
Abstract :
Seven patients with amyotrophic lateral sclerosis participated in a double-blind cross-over trial of oral physostigmine and neostigmine (10 and 45 mg/day, respectively, for 3 days). Six of the patients were also given intravenous injections (1 and 1.5 mg, respectively) of the drugs in an open trial. No significant effects on muscle strength or neurophysiological parameters were observed. |
| PubMedSearch : Aquilonius_1986_Acta.Neurol.Scand_73_628 |
| PubMedID: 3529799 |
Aquilonius SM, Askmark H, Eckernas SA, Gillberg PG, Hilton-Brown P, Rydin E, Stalberg E (1986)
Cholinesterase inhibitors lack therapeutic effect in amyotrophic lateral sclerosis. A controlled study of physostigmine versus neostigmine
Acta Neurologica Scandinavica
73 :628
Aquilonius SM, Askmark H, Eckernas SA, Gillberg PG, Hilton-Brown P, Rydin E, Stalberg E (1986)
Acta Neurologica Scandinavica
73 :628