| Title : [Structure-activity relationship in reactivators of acetylcholinesterase inhibited by phosphoric esters. XII. Hydroxyiminomethylalkylpyridine iodomethylate] - Arena_1978_Farmaco.Sci_33_324 |
| Author(s) : Arena F , Luraschi E , Grifantini M , Manna F , Parente G |
| Ref : Farmaco Sci , 33 :324 , 1978 |
|
Abstract :
2-Hydroxyiminomethyl-4-alkylpyridine methiodides were prepared and tested for their in vitro reactivating potency on phosphorylated electric eel cholinesterase. They were also tested as in vivo protecting agents: only one of the compounds, 4-methyl-2-hydroxyiminopyridine, offered a greater protection from DFP than 2-PAM, the others had little to no effect. |
| PubMedSearch : Arena_1978_Farmaco.Sci_33_324 |
| PubMedID: 738450 |
Arena F, Luraschi E, Grifantini M, Manna F, Parente G (1978)
[Structure-activity relationship in reactivators of acetylcholinesterase inhibited by phosphoric esters. XII. Hydroxyiminomethylalkylpyridine iodomethylate]
Farmaco Sci
33 :324
Arena F, Luraschi E, Grifantini M, Manna F, Parente G (1978)
Farmaco Sci
33 :324