Asylbekkyzy_2026_Microorganisms_14_

This structured critical narrative review evaluates the bacterial transformation of six selected organophosphate pesticides-chlorpyrifos, methyl parathion, parathion, diazinon, malathion, and phosalone-in relation to chemical, mechanistic, and environmental evidence. Peer-reviewed literature was searched in Scopus and PubMed for the period from 1 January 2020 to 26 August 2026 and was supplemented by backward-reference screening and forward citation tracking of foundational studies. Evidence was assessed across eight domains spanning association, tolerance, controlled dissipation, product-resolved transformation, mechanistic attribution, non-sterile-soil validation, detoxification or ecological recovery, and field readiness. The selected compounds reveal substantial differences in pathway resolution: chlorpyrifos has the most developed parent-product evidence base, methyl parathion and parathion are comparatively well characterized at the hydrolytic and enzyme levels, diazinon and malathion retain important downstream uncertainties, and phosalone remains an unresolved evidence-gap comparator. The synthesis shows that credible soil bioremediation requires convergence among parent-product kinetics, catalytic attribution, transformation-product turnover, performance beyond natural attenuation, toxicity reduction, and recovery of relevant soil or plant functions.