| Title : New Steroidal Alkaloids from Fritillaria imperialis and Their Cholinesterase Inhibiting Activities - Atta_2002_Chem.Pharm.Bull.(Tokyo)_50_1013 |
| Author(s) : Atta ur R , Akhtar MN , Choudhary MI , Tsuda Y , Sener B , Khalid A , Parvez M |
| Ref : Chem Pharm Bull (Tokyo) , 50 :1013 , 2002 |
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Abstract :
Two new cevanine steroidal alkaloids, impericine (1) and forticine (2) along with known bases delavine (3), persicanidine A (4), and imperialine (5) were isolated from the bulbs of Fritillaria imperialis. The structures of impericine (1) [(20R,22S,25S)-5alpha-cevanin-23-ene-3beta,6beta,16beta-triol] and forticine (2) [(20S,22S,25S)-5alpha-cevanine-3beta,6beta-diol] were determined with the help of spectroscopic studies. These steroidal bases showed anti-acetylcholinesterase and anti-butyrylcholinesterase inhibitory activity. |
| PubMedSearch : Atta_2002_Chem.Pharm.Bull.(Tokyo)_50_1013 |
| PubMedID: 12192128 |
Atta ur R, Akhtar MN, Choudhary MI, Tsuda Y, Sener B, Khalid A, Parvez M (2002)
New Steroidal Alkaloids from Fritillaria imperialis and Their Cholinesterase Inhibiting Activities
Chem Pharm Bull (Tokyo)
50 :1013
Atta ur R, Akhtar MN, Choudhary MI, Tsuda Y, Sener B, Khalid A, Parvez M (2002)
Chem Pharm Bull (Tokyo)
50 :1013