Aung_2020_Nat.Prod.Bioprospect_10_337

Reference

Title : Chemical Constituents from the Whole Plant of Cuscuta reflexa - Aung_2020_Nat.Prod.Bioprospect_10_337
Author(s) : Aung TTT , Xia MY , Hein PP , Tang R , Zhang DD , Yang J , Yang XF , Hu DB , Wang YH
Ref : Nat Prod Bioprospect , 10 :337 , 2020
Abstract :

Two new 2H-pyran-2-one glucosides, cuscutarosides A (1) and B (2), and one new steroidal glucoside, 7beta-methoxy-beta-sitosterol 3-O-beta-glucopyranoside (3), together with 12 known compounds (4-15) were isolated from the whole plant of Cuscuta reflexa (Convolvulaceae) collected from Myanmar. The chemical structures of these new compounds were elucidated based on extensive spectroscopic analysis. The antiobesity activity of these isolates was evaluated using porcine pancreatic lipase (PPL), and the antiplatelet aggregation activity was screened using rabbit platelets induced by thrombin, platelet-activating factor (PAF), arachidonate (AA), or collagen. 7beta-Methoxy-beta-sitosterol 3-O-beta-glucopyranoside (3) showed weak PPL inhibitory activity. Cuscutaroside A (1), its acetylated derivative (1a), and scrophenoside B (8) showed weak inhibitory activity against rabbit platelet aggregation induced by collagen. Compound 1a also showed inhibitory activity against rabbit platelet aggregation induced by AA.

PubMedSearch : Aung_2020_Nat.Prod.Bioprospect_10_337
PubMedID: 32954471

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Citations formats

Aung TTT, Xia MY, Hein PP, Tang R, Zhang DD, Yang J, Yang XF, Hu DB, Wang YH (2020)
Chemical Constituents from the Whole Plant of Cuscuta reflexa
Nat Prod Bioprospect 10 :337

Aung TTT, Xia MY, Hein PP, Tang R, Zhang DD, Yang J, Yang XF, Hu DB, Wang YH (2020)
Nat Prod Bioprospect 10 :337