Title : Chemical Constituents from the Whole Plant of Cuscuta reflexa - Aung_2020_Nat.Prod.Bioprospect_10_337 |
Author(s) : Aung TTT , Xia MY , Hein PP , Tang R , Zhang DD , Yang J , Yang XF , Hu DB , Wang YH |
Ref : Nat Prod Bioprospect , 10 :337 , 2020 |
Abstract :
Two new 2H-pyran-2-one glucosides, cuscutarosides A (1) and B (2), and one new steroidal glucoside, 7beta-methoxy-beta-sitosterol 3-O-beta-glucopyranoside (3), together with 12 known compounds (4-15) were isolated from the whole plant of Cuscuta reflexa (Convolvulaceae) collected from Myanmar. The chemical structures of these new compounds were elucidated based on extensive spectroscopic analysis. The antiobesity activity of these isolates was evaluated using porcine pancreatic lipase (PPL), and the antiplatelet aggregation activity was screened using rabbit platelets induced by thrombin, platelet-activating factor (PAF), arachidonate (AA), or collagen. 7beta-Methoxy-beta-sitosterol 3-O-beta-glucopyranoside (3) showed weak PPL inhibitory activity. Cuscutaroside A (1), its acetylated derivative (1a), and scrophenoside B (8) showed weak inhibitory activity against rabbit platelet aggregation induced by collagen. Compound 1a also showed inhibitory activity against rabbit platelet aggregation induced by AA. |
PubMedSearch : Aung_2020_Nat.Prod.Bioprospect_10_337 |
PubMedID: 32954471 |
Aung TTT, Xia MY, Hein PP, Tang R, Zhang DD, Yang J, Yang XF, Hu DB, Wang YH (2020)
Chemical Constituents from the Whole Plant of Cuscuta reflexa
Nat Prod Bioprospect
10 :337
Aung TTT, Xia MY, Hein PP, Tang R, Zhang DD, Yang J, Yang XF, Hu DB, Wang YH (2020)
Nat Prod Bioprospect
10 :337