| Title : Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining - Awakawa_2013_Chembiochem_14_2095 |
| Author(s) : Awakawa T , Yang XL , Wakimoto T , Abe I |
| Ref : Chembiochem , 14 :2095 , 2013 |
|
Abstract :
Induced production of PKS-NRPS metabolites: the genome mining approach is useful for obtaining new compounds. We activated a dormant PKS-NRPS gene cluster in Aspergillus niger ATCC 1015 by expressing its dedicated transcriptional activator (PynR). As a result, the transformant expressing pynR produced a new pyranonigrin compound that we have named pyranonigirin E. |
| PubMedSearch : Awakawa_2013_Chembiochem_14_2095 |
| PubMedID: 24106156 |
| Gene_locus related to this paper: aspnc-pyni |
| Gene_locus | aspnc-pyni |
Awakawa T, Yang XL, Wakimoto T, Abe I (2013)
Pyranonigrin E: a PKS-NRPS hybrid metabolite from Aspergillus niger identified by genome mining
Chembiochem
14 :2095
Awakawa T, Yang XL, Wakimoto T, Abe I (2013)
Chembiochem
14 :2095