Title : New bioactive steroidal alkaloids from Buxus hyrcana - Babar_2006_Steroids_71_1045 |
Author(s) : Babar ZU , Ata A , Meshkatalsadat MH |
Ref : Steroids , 71 :1045 , 2006 |
Abstract :
Phytochemical studies on the crude methanolic extract of Buxus hyrcana, collected from Iran, resulted in the isolation of two new steroidal alkaloids, (+)-O6-buxafurandiene (1) and (+)-7-deoxy-O6-buxafurandiene (2) along with four known steroidal bases, (+)-benzoylbuxidienine (3), (+)-buxapapillinine (4), (+)-buxaquamarine (5) and (+)-irehine (6). The structures of these new and known compounds were established with the aid of extensive NMR spectroscopic studies. Compounds 1 and 2 belong to the rarely occurring class of Buxus alkaloids having a tetrahydrofuran ring incorporated in their structures. Compounds 1-6 exhibited acetylcholinesterase enzyme inhibitory activity. |
PubMedSearch : Babar_2006_Steroids_71_1045 |
PubMedID: 17049575 |
Babar ZU, Ata A, Meshkatalsadat MH (2006)
New bioactive steroidal alkaloids from Buxus hyrcana
Steroids
71 :1045
Babar ZU, Ata A, Meshkatalsadat MH (2006)
Steroids
71 :1045