| Title : Protection of Brain Acetylcholinesterase against Inhibition with VX Agent in Laboratory Rats - Bajgar_2009_Mil.Med.Sci.Lett_78_60 |
| Author(s) : Bajgar J |
| Ref : Military Medical Science Letters , 78 :60 , 2009 |
|
Abstract :
Protective effect of cholinesterase reversible inhibitors tacrin, and pyridostigmine alone or in combination with different drugs against acetylcholinesterase inhibition in the pontomedullar area and cerebellum of rats caused by VX agent in vivo was studied as well as survival of animals pretreated with different combinations of the drugs used. The best prophylactic effect was observed for combination of pyridostigmine (or tacrin) with benactyzine, trihexyphenidyle and HI-6. However, tacrine alone or in other combinations had not better prophylactic effect in comparison with these combinations containing pyridostigmine. |
| PubMedSearch : Bajgar_2009_Mil.Med.Sci.Lett_78_60 |
| PubMedID: |
Bajgar J (2009)
Protection of Brain Acetylcholinesterase against Inhibition with VX Agent in Laboratory Rats
Military Medical Science Letters
78 :60
Bajgar J (2009)
Military Medical Science Letters
78 :60