| Title : Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides - Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 |
| Author(s) : Beebe X , Yang F , Bui MH , Mitten MJ , Ma Z , Nilius AM , Djuric SW |
| Ref : Bioorganic & Medicinal Chemistry Lett , 14 :2417 , 2004 |
|
Abstract :
A series of novel 6-O-arylpropargyl-9-oxime-ketolides was synthesized and evaluated against various pathogens. These new compounds show promising in vitro antibacterial potency and in vivo efficacy against macrolide resistant strains. |
| PubMedSearch : Beebe_2004_Bioorg.Med.Chem.Lett_14_2417 |
| PubMedID: 15109624 |
Beebe X, Yang F, Bui MH, Mitten MJ, Ma Z, Nilius AM, Djuric SW (2004)
Synthesis and antibacterial activity of 6-O-arylpropargyl-9-oxime-11,12-carbamate ketolides
Bioorganic & Medicinal Chemistry Lett
14 :2417
Beebe X, Yang F, Bui MH, Mitten MJ, Ma Z, Nilius AM, Djuric SW (2004)
Bioorganic & Medicinal Chemistry Lett
14 :2417