Title : Changes in voltage dependence of NMDA currents during development - Ben-Ari_1988_Neurosci.Lett_94_88 |
Author(s) : Ben-Ari Y , Cherubini E , Krnjevic K |
Ref : Neuroscience Letters , 94 :88 , 1988 |
Abstract :
N-Methyl-D-aspartate (NMDA), applied by superfusion to hippocampal slices evokes comparable peak inward currents in CA3 pyramidal cells of adult and 0-10 day-old rats. However, NMDA current-voltage plots from immature neurones do not consistently show the region of negative slope conductance characteristic of adult. Therefore at a critical stage of development, NMDA activation may elicit substantial inward currents and Ca2+ influx at resting membrane potential. |
PubMedSearch : Ben-Ari_1988_Neurosci.Lett_94_88 |
PubMedID: 3071749 |
Ben-Ari Y, Cherubini E, Krnjevic K (1988)
Changes in voltage dependence of NMDA currents during development
Neuroscience Letters
94 :88
Ben-Ari Y, Cherubini E, Krnjevic K (1988)
Neuroscience Letters
94 :88