Bernieri_2018_Chemosphere_218_425

Reference

Title : Occupational exposure to pesticides and thyroid function in Brazilian soybean farmers - Bernieri_2018_Chemosphere_218_425
Author(s) : Bernieri T , Rodrigues D , Barbosa IR , Ardenghi PG , Basso da Silva L
Ref : Chemosphere , 218 :425 , 2018
Abstract :

INTRODUCTION: Agriculture production has been supported especially by the use of pesticides for crop protection and pest control. Although the agricultural production has been increased by pesticides use, these substances also reach non-target organisms and may become a risk to the health of farmers. Several epidemiological studies in human have investigated the association between exposure to pesticides and altered serum levels of thyroid hormones, reporting both positive and negative results. Overall, the impact of pesticides on human thyroid function is still limited. OBJECTIVE: The aim of this study was to access serum levels of free thyroxin (FT4), total triiodothyronine (TT3), thyroid-stimulating hormone (TSH), and butyrylcholinesterase (BChE) in soybean farmers in southern Brazil. METHODS: The exposed group was composed by 46 rural workers and 27 subjects not exposed to pesticides composed the control group. All subjects had blood samples collected by venipuncture in order to analyze the serum levels of FT4, TT3, TSH and BChE. RESULTS: The results showed a significant decreasing in TSH and increasing in TT3 and FT4 in rural workers, compared to control group. BChE levels were lower in exposed group than in control group. The results suggest that farmers are exposed to mixtures of pesticides with endocrine disruptor properties.

PubMedSearch : Bernieri_2018_Chemosphere_218_425
PubMedID: 30476775

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Citations formats

Bernieri T, Rodrigues D, Barbosa IR, Ardenghi PG, Basso da Silva L (2018)
Occupational exposure to pesticides and thyroid function in Brazilian soybean farmers
Chemosphere 218 :425

Bernieri T, Rodrigues D, Barbosa IR, Ardenghi PG, Basso da Silva L (2018)
Chemosphere 218 :425