| Title : Muscarinic receptor subtypes and the selectivity of agonists and antagonists - Birdsall_1988_Pharmacology_37 Suppl 1_22 |
| Author(s) : Birdsall NJ , Curtis CA , Eveleigh P , Hulme EC , Pedder EK , Poyner D , Wheatley M |
| Ref : Pharmacology , 37 Suppl 1 :22 , 1988 |
|
Abstract :
Receptors may be grouped into superfamilies, according to their mechanism. Muscarinic receptors belong to one such superfamily, that of the G-protein coupled receptors. Subtypes of muscarinic receptors may be defined according to their primary amino acid sequence, their mechanism and their pharmacology. However, there is as yet no consistent scheme to explain the pharmacology and function of each molecular subtype. The pharmacological tools which distinguish between muscarinic receptor subtypes are described and the emerging evidence for the location of the ligand binding site is discussed. |
| PubMedSearch : Birdsall_1988_Pharmacology_37 Suppl 1_22 |
| PubMedID: 2467316 |
Birdsall NJ, Curtis CA, Eveleigh P, Hulme EC, Pedder EK, Poyner D, Wheatley M (1988)
Muscarinic receptor subtypes and the selectivity of agonists and antagonists
Pharmacology
37 Suppl 1 :22
Birdsall NJ, Curtis CA, Eveleigh P, Hulme EC, Pedder EK, Poyner D, Wheatley M (1988)
Pharmacology
37 Suppl 1 :22