| Title : Proposed acquisition of an animal protein domain by bacteria - Bork_1992_Proc.Natl.Acad.Sci.U.S.A_89_8990 |
| Author(s) : Bork P , Doolittle RF |
| Ref : Proc Natl Acad Sci U S A , 89 :8990 , 1992 |
|
Abstract :
A systematic screen of a protein sequence data base confirms that the fibronectin type III (Fn3) domain is widely distributed among animal proteins and occurs also in several bacterial carbohydrate-splitting enzymes. The motif has yet to be identified in proteins from plants or fungi. All indications are that the bacterial sequences are much too similar to the animal type to be the result of conventional vertical descent. Rather, it is likely that the bacterial units were initially acquired from an animal source and are being spread further by horizontal transfers between distantly related bacteria. |
| PubMedSearch : Bork_1992_Proc.Natl.Acad.Sci.U.S.A_89_8990 |
| PubMedID: 1409594 |
| Gene_locus related to this paper: alcfa-phb |
| Gene_locus | alcfa-phb |
Bork P, Doolittle RF (1992)
Proposed acquisition of an animal protein domain by bacteria
Proc Natl Acad Sci U S A
89 :8990
Bork P, Doolittle RF (1992)
Proc Natl Acad Sci U S A
89 :8990