| Title : Improved biocatalysts by directed evolution and rational protein design - Bornscheuer_2001_Curr.Opin.Chem.Biol_5_137 |
| Author(s) : Bornscheuer UT , Pohl M |
| Ref : Curr Opin Chemical Biology , 5 :137 , 2001 |
|
Abstract :
The efficient application of biocatalysts requires the availability of suitable enzymes with high activity and stability under process conditions, desired substrate selectivity and high enantioselectivity. However, wild-type enzymes often need to be optimized to fulfill these requirements. Two rather contradictory tools can be used on a molecular level to create tailor-made biocatalysts: directed evolution and rational protein design. |
| PubMedSearch : Bornscheuer_2001_Curr.Opin.Chem.Biol_5_137 |
| PubMedID: 11282339 |
Bornscheuer UT, Pohl M (2001)
Improved biocatalysts by directed evolution and rational protein design
Curr Opin Chemical Biology
5 :137
Bornscheuer UT, Pohl M (2001)
Curr Opin Chemical Biology
5 :137