| Title : Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia - Brufani_1986_Eur.J.Biochem_157_115 |
| Author(s) : Brufani M , Marta M , Pomponi M |
| Ref : European Journal of Biochemistry , 157 :115 , 1986 |
|
Abstract :
The anticholinesterase activity of a new carbamate, heptylphysostigmine, was studied in vitro. This compound is a competitive inhibitor of acetylcholinesterase (or true cholinesterase) having Ki = (1 +/- 0.5) X 10(-7) M. The inhibition was instantaneous at the onset and did not diminish with prolonged incubation of the drug and enzyme. |
| PubMedSearch : Brufani_1986_Eur.J.Biochem_157_115 |
| PubMedID: 3709528 |
Brufani M, Marta M, Pomponi M (1986)
Anticholinesterase activity of a new carbamate, heptylphysostigmine, in view of its use in patients with Alzheimer-type dementia
European Journal of Biochemistry
157 :115
Brufani M, Marta M, Pomponi M (1986)
European Journal of Biochemistry
157 :115