| Title : Aging and reactivatability of plaice cholinesterase inhibited by soman and its stereoisomers - Bucht_1984_Biochem.Pharmacol_33_3573 |
| Author(s) : Bucht G , Puu G |
| Ref : Biochemical Pharmacology , 33 :3573 , 1984 |
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Abstract :
A simple and rapid method to study aging of soman-inhibited cholinesterases was developed. The method was applied to study the aging characteristics of soman-inhibited cholinesterase from the muscles of the plaice (Pleuronectes platessa). The orientation of the soman molecule in the active site is decisive both for the rate of aging and the degree of reactivation of unaged enzyme, a conclusion reached by using soman stereoisomers. Fluoride ions were found to affect reactivatability as well as aging rate. |
| PubMedSearch : Bucht_1984_Biochem.Pharmacol_33_3573 |
| PubMedID: 6508819 |
Bucht G, Puu G (1984)
Aging and reactivatability of plaice cholinesterase inhibited by soman and its stereoisomers
Biochemical Pharmacology
33 :3573
Bucht G, Puu G (1984)
Biochemical Pharmacology
33 :3573