| Title : A liver-specific isoform of the betaine\/GABA transporter in the rat: cDNA sequence and organ distribution - Burnham_1996_Biochim.Biophys.Acta_2_4 |
| Author(s) : Burnham CE , Buerk B , Schmidt C , Bucuvalas JC |
| Ref : Biochimica & Biophysica Acta , 2 :4 , 1996 |
|
Abstract :
We report the cloning of a 2.2 kb cDNA encoding a Na(+)-and Cl- dependent betaine/GABA (gamma-aminobutyric acid) transporter from rat liver poly(A+) RNA. 5'-RACE revealed an additional 355 bases 5' to the 2.2 kb cDNA sequence. Northern analysis demonstrated two (2.2 kb and 2.6 kb) mRNA isoforms in rat liver. Betaine transporter mRNA was also detected in the brain, spleen, lung, and kidney using the 2.2 kb cDNA clone as a probe. Only the 2.6 kb mRNA from the liver hybridized with the 5'-RACE product. |
| PubMedSearch : Burnham_1996_Biochim.Biophys.Acta_2_4 |
| PubMedID: 8865807 |
Burnham CE, Buerk B, Schmidt C, Bucuvalas JC (1996)
A liver-specific isoform of the betaine\/GABA transporter in the rat: cDNA sequence and organ distribution
Biochimica & Biophysica Acta
2 :4
Burnham CE, Buerk B, Schmidt C, Bucuvalas JC (1996)
Biochimica & Biophysica Acta
2 :4