| Title : Analysis of Amaryllidaceae alkaloids from Zephyranthes robusta by GC-MS and their cholinesterase activity - Cahlikova_2010_Nat.Prod.Commun_5_1201 |
| Author(s) : Cahlikova L , Kulhankova A , Urbanova K , Valterova I , Macakova K , Kunes J |
| Ref : Nat Prod Commun , 5 :1201 , 2010 |
|
Abstract :
From the bulbs of Zephyranthes robusta Baker (Amaryllidaceae), seven known compounds, belonging to four structural types of Amaryllidaceae alkaloids, were identified and quantified by GC-MS. The alkaloid extract from the bulbs showed promising acetylcholinesterase and butyrylcholinesterase inhibitory activities against HuAChE (IC50 = 35.9 +/- 3.5 microg/mL) and HuBuChE (IC50 = 190.9 +/- 8.2 microg/mL). |
| PubMedSearch : Cahlikova_2010_Nat.Prod.Commun_5_1201 |
| PubMedID: 20839618 |
Cahlikova L, Kulhankova A, Urbanova K, Valterova I, Macakova K, Kunes J (2010)
Analysis of Amaryllidaceae alkaloids from Zephyranthes robusta by GC-MS and their cholinesterase activity
Nat Prod Commun
5 :1201
Cahlikova L, Kulhankova A, Urbanova K, Valterova I, Macakova K, Kunes J (2010)
Nat Prod Commun
5 :1201