| Title : Monoterpene indole alkaloids from the stem bark of Mitragyna diversifolia and their acetylcholine esterase inhibitory effects - Cao_2013_Phytochemistry_96_389 |
| Author(s) : Cao XF , Wang JS , Wang XB , Luo J , Wang HY , Kong LY |
| Ref : Phytochemistry , 96 :389 , 2013 |
|
Abstract :
Five monoterpene indole alkaloids, mitradiversifoline, with a unique rearranged skeleton, specionoxeine-N(4)-oxide, 7-hydroxyisopaynantheine, 3-dehydropaynantheine, and 3-isopaynantheine-N(4)-oxide, and 10 known ones, were isolated from Mitragyna diversifolia. All the isolates were evaluated for their inhibition of acetylcholinesterase activities, and four showed moderate activities, with IC50 values of 4.1, 5.2, 10.2, and 10.3muM, respectively. |
| PubMedSearch : Cao_2013_Phytochemistry_96_389 |
| PubMedID: 24169379 |
Cao XF, Wang JS, Wang XB, Luo J, Wang HY, Kong LY (2013)
Monoterpene indole alkaloids from the stem bark of Mitragyna diversifolia and their acetylcholine esterase inhibitory effects
Phytochemistry
96 :389
Cao XF, Wang JS, Wang XB, Luo J, Wang HY, Kong LY (2013)
Phytochemistry
96 :389