Caratsch_1982_Proc.R.Soc.Lond.B.Biol.Sci_215_365

Reference

Title : Antibodies to beta-bungarotoxin and its phospholipase inactive derivative - Caratsch_1982_Proc.R.Soc.Lond.B.Biol.Sci_215_365
Author(s) : Caratsch CG , Maranda B , Miledi R , Strong PN
Ref : Proc R Soc Lond B Biol Sci , 215 :365 , 1982
Abstract :

Antisera were raised against the presynaptic neurotoxin beta-bungarotoxin and against its phospholipase-inactive derivative, modified by reaction with p-bromophenacyl bromide. The cross-reactivity of the antisera to other phospholipase A2 enzymes and polypeptide neurotoxins was examined. The antisera inhibited both the neurotoxic effects of beta-bungarotoxin at the frog motor endplate and the enzymatic activity of the toxin on model phospholipid membranes, although it is unlikely that the catalytic active centre is the locus of any major determinant.

PubMedSearch : Caratsch_1982_Proc.R.Soc.Lond.B.Biol.Sci_215_365
PubMedID: 6182570

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Citations formats

Caratsch CG, Maranda B, Miledi R, Strong PN (1982)
Antibodies to beta-bungarotoxin and its phospholipase inactive derivative
Proc R Soc Lond B Biol Sci 215 :365

Caratsch CG, Maranda B, Miledi R, Strong PN (1982)
Proc R Soc Lond B Biol Sci 215 :365