Chang_1991_Trop.Med.Parasitol_42_95

Reference

Title : Efficacy of diethylcarbamazine and pirimiphos-methyl residual spraying in controlling brugian filariasis - Chang_1991_Trop.Med.Parasitol_42_95
Author(s) : Chang MS , Ho BC , Chan KL
Ref : Trop Med Parasitol , 42 :95 , 1991
Abstract : A control programme against subperiodic brugian filariasis was implemented in three villages, (Kg. Ampungan, Kg. Sebangkoi and Kg. Sebamban) in Sarawak, Malaysia. In Kampong Ampungan, the mass administration of diethylcarbamazine (DEC-citrate) combined with residual house spraying of pirimiphos-methyl reduced microfilarial rate to 8% of the pre-treatment level and microfilarial density (MfD50) to 44% of the pre-treatment level over a period of four years. In Kampong Sebangkoi and Kampong Sebamban, where only mass DEC therapy was applied, the microfilarial rate and MfD50 declined distinctly in the second blood survey but increased gradually in two subsequent follow-up blood surveys. In Kg, Ampungan, we observed a significant reduction of infective biting rate (88.3%), infection rate (62.5%) and transmission potential (88.1%) of Mansonia bonneae at the fourth spray round. The corresponding reduction rates in Kg. Sebangkoi and Kg. Sebamban were 35.3%, 26.7%, 42.2% and 24%, 30.8% and 15.4% respectively. The biting density of the vector was reduced by 79.8% indoors and 31.8% outdoors at the sprayed village, while only a slight decrease in densities (17.9% indoors and 12.4% outdoors) was observed at the unsprayed village. Bioassay tests revealed that pirimiphos-methyl had a substantial fumigant effect on the vector. The integrated control measure in controlling subperiodic brugian filariasis is discussed.
ESTHER : Chang_1991_Trop.Med.Parasitol_42_95
PubMedSearch : Chang_1991_Trop.Med.Parasitol_42_95
PubMedID: 1680246

Related information

Citations formats

Chang MS, Ho BC, Chan KL (1991)
Efficacy of diethylcarbamazine and pirimiphos-methyl residual spraying in controlling brugian filariasis
Trop Med Parasitol 42 :95

Chang MS, Ho BC, Chan KL (1991)
Trop Med Parasitol 42 :95

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    [paper] => Chang_1991_Trop.Med.Parasitol_42_95
    [author] => Chang MS || Ho BC || Chan KL
    [year] => 1991
    [title] => Efficacy of diethylcarbamazine and pirimiphos-methyl residual spraying in controlling brugian filariasis
    [journal] => Trop Med Parasitol
    [volume] => 42
    [page] => 95
    [medline] => 1680246
    [abstract] => Chang_1991_Trop.Med.Parasitol_42_95
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            [content] => A control programme against subperiodic brugian filariasis was implemented in three villages, (Kg. Ampungan, Kg. Sebangkoi and Kg. Sebamban) in Sarawak, Malaysia. In Kampong Ampungan, the mass administration of diethylcarbamazine (DEC-citrate) combined with residual house spraying of pirimiphos-methyl reduced microfilarial rate to 8% of the pre-treatment level and microfilarial density (MfD50) to 44% of the pre-treatment level over a period of four years. In Kampong Sebangkoi and Kampong Sebamban, where only mass DEC therapy was applied, the microfilarial rate and MfD50 declined distinctly in the second blood survey but increased gradually in two subsequent follow-up blood surveys. In Kg, Ampungan, we observed a significant reduction of infective biting rate (88.3%), infection rate (62.5%) and transmission potential (88.1%) of Mansonia bonneae at the fourth spray round. The corresponding reduction rates in Kg. Sebangkoi and Kg. Sebamban were 35.3%, 26.7%, 42.2% and 24%, 30.8% and 15.4% respectively. The biting density of the vector was reduced by 79.8% indoors and 31.8% outdoors at the sprayed village, while only a slight decrease in densities (17.9% indoors and 12.4% outdoors) was observed at the unsprayed village. Bioassay tests revealed that pirimiphos-methyl had a substantial fumigant effect on the vector. The integrated control measure in controlling subperiodic brugian filariasis is discussed.
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