| Title : Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors - Changeux_2001_Curr.Opin.Neurobiol_11_369 |
| Author(s) : Changeux J , Edelstein SJ |
| Ref : Current Opinion in Neurobiology , 11 :369 , 2001 |
|
Abstract :
Recent chemical and advanced structural studies on site-directed and naturally occurring pathological mutants of individual members of the multigene family of nicotinic acetylcholine receptors have yielded structure-function relationships supporting indirect 'allosteric' interactions between the acetylcholine-binding sites and the ion channel in signal transduction. |
| PubMedSearch : Changeux_2001_Curr.Opin.Neurobiol_11_369 |
| PubMedID: 11399437 |
Changeux J, Edelstein SJ (2001)
Allosteric mechanisms in normal and pathological nicotinic acetylcholine receptors
Current Opinion in Neurobiology
11 :369
Changeux J, Edelstein SJ (2001)
Current Opinion in Neurobiology
11 :369