| Title : HPLC-guided isolation and characterization of monoterpene glycosides from the dried roots bark of Paeonia suffruticosa Andr - Chen_2025_Fitoterapia__106900 |
| Author(s) : Chen L , Cao YG , Liu YL , Chen X , Lu D , Zhao BX , Niu Y , Zheng XK , Feng WS |
| Ref : Fitoterapia , :106900 , 2025 |
|
Abstract :
Three undescribed monoterpene glycosides (1-3), along with seventeen known analogues (4-20), were isolated from the dried roots bark of Paeonia x suffruticosa Andr. based on high-performance liquid chromatography (HPLC) analysis and small molecule accurate recognition technology (SMART). Their structures were assigned by spectroscopic techniques, and the absolute configurations of compounds 1-3 were elucidated by comparing the computed and experimental electronic circular dichroism (ECD) spectra. Additionally, compound 2 exhibited moderate inhibitory effect on acetylcholinesterase (AChE) with the IC(50) value of 18.54 +/- 2.60 microM. Compound 13 showed significantly activity on DPPH with the IC(50) value of 9.04 +/- 2.33 microM. |
| PubMedSearch : Chen_2025_Fitoterapia__106900 |
| PubMedID: 41005499 |
Chen L, Cao YG, Liu YL, Chen X, Lu D, Zhao BX, Niu Y, Zheng XK, Feng WS (2025)
HPLC-guided isolation and characterization of monoterpene glycosides from the dried roots bark of Paeonia suffruticosa Andr
Fitoterapia
:106900
Chen L, Cao YG, Liu YL, Chen X, Lu D, Zhao BX, Niu Y, Zheng XK, Feng WS (2025)
Fitoterapia
:106900