Title : Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis - Chiantore_2016_J.Cancer.Res.Clin.Oncol_142_1751 |
Author(s) : Chiantore MV , Mangino G , Iuliano M , Zangrillo MS , De Lillis I , Vaccari G , Accardi R , Tommasino M , Columba Cabezas S , Federico M , Fiorucci G , Romeo G |
Ref : J Cancer Research Clin Oncol , 142 :1751 , 2016 |
Abstract :
PURPOSE: Human papillomaviruses (HPVs) are the causative agents of cervical cancer and are also associated with other types of cancers. HPVs can modulate microRNAs (miRNAs) expressed by infected cells. The production of extracellular vesicles is deregulated in cancer, and their cargo delivered to the microenvironment can promote tumorigenesis. The involvement of HPV oncoproteins on miRNA expression in cells and exosomes was analyzed in keratinocytes transduced with E6 and E7 from mucosal HPV-16 or cutaneous HPV-38 (K16 and K38). |
PubMedSearch : Chiantore_2016_J.Cancer.Res.Clin.Oncol_142_1751 |
PubMedID: 27300513 |
Chiantore MV, Mangino G, Iuliano M, Zangrillo MS, De Lillis I, Vaccari G, Accardi R, Tommasino M, Columba Cabezas S, Federico M, Fiorucci G, Romeo G (2016)
Human papillomavirus E6 and E7 oncoproteins affect the expression of cancer-related microRNAs: additional evidence in HPV-induced tumorigenesis
J Cancer Research Clin Oncol
142 :1751
Chiantore MV, Mangino G, Iuliano M, Zangrillo MS, De Lillis I, Vaccari G, Accardi R, Tommasino M, Columba Cabezas S, Federico M, Fiorucci G, Romeo G (2016)
J Cancer Research Clin Oncol
142 :1751