| Title : Synthetic studies on the solanacol ABC ring system by cation-initiated cascade cyclization: implications for strigolactone biosynthesis - Chojnacka_2011_Org.Biomol.Chem_9_5350 |
| Author(s) : Chojnacka K , Santoro S , Awartani R , Richards NG , Himo F , Aponick A |
| Ref : Org Biomol Chem , 9 :5350 , 2011 |
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Abstract :
We report a new method for constructing the ABC ring system of strigolactones, in a single step from a simple linear precursor by acid-catalyzed double cyclization. The reaction proceeds with a high degree of stereochemical control, which can be qualitatively rationalized using DFT calculations. Our concise synthetic approach offers a new model for thinking about the (as yet) unknown chemistry that is employed in the biosynthetic pathways leading to this class of plant hormones. |
| PubMedSearch : Chojnacka_2011_Org.Biomol.Chem_9_5350 |
| PubMedID: 21706088 |
| Inhibitor | Solanacol |
Chojnacka K, Santoro S, Awartani R, Richards NG, Himo F, Aponick A (2011)
Synthetic studies on the solanacol ABC ring system by cation-initiated cascade cyclization: implications for strigolactone biosynthesis
Org Biomol Chem
9 :5350
Chojnacka K, Santoro S, Awartani R, Richards NG, Himo F, Aponick A (2011)
Org Biomol Chem
9 :5350