Cogun_2012_J.Biochem.Mol.Toxicol_26_117

Reference

Title : Protective effect of selenium against mercury-induced toxicity on hematological and biochemical parameters of Oreochromis niloticus - Cogun_2012_J.Biochem.Mol.Toxicol_26_117
Author(s) : Cogun HY , Firat O , Yuzereroglu TA , Gok G , Kargin F , Kotemen Y
Ref : J Biochem Mol Toxicol , 26 :117 , 2012
Abstract :

In this study, to identify mercury (Hg) toxicity and whether selenium (Se) has any role in alleviation of this toxicity, it was investigated the changes in hematological and serum biochemical parameters of Oreochromis niloticus. Fish were exposed to 0.01 and 0.1 mg/L Hg and 0.01 mg/L Hg + 0.1 mg/L Se and 0.1 mg/L Hg + 1.0 mg/L Se for 7 and 14 days. The exposure of O. niloticus to Hg alone resulted in decreases in red blood cell, white blood cell, hemoglobin, hematocrit values, and cholinesterase activity while it increased in alanine aminotransferase and aspartate aminotransferase activities and cortisol and glucose levels. Se, in combination with Hg, partially or totally caused an alleviation for the toxic effect of Hg on the above mentioned hematological and biochemical parameters. The results of our study showed that Se has a protective effect against toxicity induced by Hg.

PubMedSearch : Cogun_2012_J.Biochem.Mol.Toxicol_26_117
PubMedID: 22162128

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Citations formats

Cogun HY, Firat O, Yuzereroglu TA, Gok G, Kargin F, Kotemen Y (2012)
Protective effect of selenium against mercury-induced toxicity on hematological and biochemical parameters of Oreochromis niloticus
J Biochem Mol Toxicol 26 :117

Cogun HY, Firat O, Yuzereroglu TA, Gok G, Kargin F, Kotemen Y (2012)
J Biochem Mol Toxicol 26 :117