| Title : Inhibition kinetics of brain butyrylcholinesterase by Cd2+ and Zn2+, Ca2+ or Mg2+ reactivates the inhibited enzyme - Cokugras_1993_Int.J.Biochem_25_1115 |
| Author(s) : Cokugras AN , Tezcan EF |
| Ref : International Journal of Biochemistry , 25 :1115 , 1993 |
|
Abstract :
1. The inhibition kinetics of sheep brain butyrylcholinesterase (BChE) (acylcholine acylhydrolase, EC 3.1.1.8) by Cd2+ and Zn2+ has been studied. 2. KS has been determined as 0.14 mM. Cd2+ and Zn2+ were the hyperbolic mixed-type inhibitors of BChE. Ca2+ and Mg2+ had no effect on the enzyme activity in the experimental conditions. 3. But when the enzyme was inhibited by 0.1 mM Cd2+ or Zn2+, Ca2+ and Mg2+ reactivated the inhibited form of BChE. |
| PubMedSearch : Cokugras_1993_Int.J.Biochem_25_1115 |
| PubMedID: 8405652 |
Cokugras AN, Tezcan EF (1993)
Inhibition kinetics of brain butyrylcholinesterase by Cd2+ and Zn2+, Ca2+ or Mg2+ reactivates the inhibited enzyme
International Journal of Biochemistry
25 :1115
Cokugras AN, Tezcan EF (1993)
International Journal of Biochemistry
25 :1115