Consolo_1997_Brain.Res_756_174

Reference

Title : Galparan induces in vivo acetylcholine release in the frontal cortex - Consolo_1997_Brain.Res_756_174
Author(s) : Consolo S , Baldi G , Nannini L , Uboldi MC , Pooga M , Langel U , Bartfai T
Ref : Brain Research , 756 :174 , 1997
Abstract :

The chimeric peptide galparan (galanin(1-13)-mastoparan) induced the in vivo release of acetylcholine in the frontal cortex of rats when injected intracerebroventricularly, i.c.v. The ACh-releasing effects of galparan are reversible, dose-dependent, and not exerted at galanin receptors or at sites where mastoparan acts. Pertussis toxin pretreatment (i.c.v.) of the rats for 96 h prior to injection of galparan or of mastoparan completely prevented the ACh-releasing effects of both galparan and mastoparan. It appears that galparan acts at a novel site in the release of ACh in the cerebral cortex in vivo.

PubMedSearch : Consolo_1997_Brain.Res_756_174
PubMedID: 9187329

Related information

Citations formats

Consolo S, Baldi G, Nannini L, Uboldi MC, Pooga M, Langel U, Bartfai T (1997)
Galparan induces in vivo acetylcholine release in the frontal cortex
Brain Research 756 :174

Consolo S, Baldi G, Nannini L, Uboldi MC, Pooga M, Langel U, Bartfai T (1997)
Brain Research 756 :174