| Title : The nicotinic acetylcholine receptor: structure and autoimmune pathology - Conti-Tronconi_1994_Crit.Rev.Biochem.Mol.Biol_29_69 |
| Author(s) : Conti-Tronconi BM , McLane KE , Raftery MA , Grando SA , Protti MP |
| Ref : Crit Rev Biochem Mol Biol , 29 :69 , 1994 |
|
Abstract :
The nicotinic acetylcholine receptors (AChR) are presently the best-characterized neurotransmitter receptors. They are pentamers of homologous or identical subunits, symmetrically arranged to form a transmembrane cation channel. The AChR subunits form a family of homologous proteins, derived from a common ancestor. An autoimmune response to muscle AChR causes the disease myasthenia gravis. This review summarizes recent developments in the understanding of the AChR structure and its molecular recognition by the immune system in myasthenia. |
| PubMedSearch : Conti-Tronconi_1994_Crit.Rev.Biochem.Mol.Biol_29_69 |
| PubMedID: 8026215 |
Conti-Tronconi BM, McLane KE, Raftery MA, Grando SA, Protti MP (1994)
The nicotinic acetylcholine receptor: structure and autoimmune pathology
Crit Rev Biochem Mol Biol
29 :69
Conti-Tronconi BM, McLane KE, Raftery MA, Grando SA, Protti MP (1994)
Crit Rev Biochem Mol Biol
29 :69